IGF1-LR3

$109.99

IGF-1 LR3 is a modified growth factor with prolonged activity (20-30h) for studying muscle protein synthesis, satellite cell activation, and recovery processes.

1 mg

Select Quantity:

SKU IGF Category

Description

IGF-1 Long R3 is an enhanced 83-amino acid variant of natural IGF-1, engineered with:
✔️ Extended 20-30 hour half-life (vs 12h for standard IGF-1)
✔️ 13 additional N-terminal amino acids for receptor protection
✔️ 10x greater bioavailability than native IGF-1

Mechanisms of Action:
• Binds IGF-1 receptors to activate mTOR pathways
• Stimulates satellite cell proliferation (muscle stem cells)
• Increases protein synthesis while reducing catabolism

Research Applications:
• Muscle hypertrophy studies
• Injury recovery models
• Age-related sarcopenia research

For research purposes only. Not for human consumption.

Injection Guide

**1. Understanding Peptide Injections**

Peptides are typically administered subcutaneously (SQ), meaning they are injected just beneath the skin into the fatty tissue. Some peptides may also be administered intramuscularly (IM) depending on their intended effects.


**Common Injection Sites for Subcutaneous (SQ) Injections:**

  • **Upper Arm:** At least 3 inches (7.5 cm) below the shoulder and 3 inches (7.5 cm) above the elbow.
    • **Outer Thigh:** On the lateral (outer) side of the thigh, avoiding bony areas.
    • **Abdomen:** Below the ribs and above the hip bones, ensuring at least 2 inches (5 cm) away from the belly button.
    Tip: Select an area where you can pinch 1 to 2 inches (2.5 to 5 cm) of skin to ensure proper subcutaneous administration.


**2. Preparation Before Injection**


**Gather Supplies:**

  • Alcohol swabs
    • Sterile insulin or 1mL syringes (typically 29-31 gauge, ½-inch needle)
    • Peptide vial (reconstituted with bacteriostatic water)
    • Sharps container for needle disposal


**Wash Hands & Clean the Injection Site:**

  • Wash hands thoroughly with soap and warm water.
    • Clean the injection site with an alcohol swab and allow it to air dry.


**3. Drawing Up the Peptide**

  1. **Reconstitute Peptides (If Necessary):** Most peptides are supplied in lyophilized (powder) form and must be reconstituted with bacteriostatic water before use.
    2. **Mix Gently:** Do not shake the vial. Instead, roll it gently between your fingers until the powder dissolves completely.
    3. **Withdraw the Correct Dose:** Use a sterile syringe to draw the prescribed dose of peptide, hold the syringe upright, and tap gently to remove any air bubbles before administering.


**4. Performing the Injection**


**Subcutaneous Injection Steps:**

  1. Pinch 1-2 inches of skin at the chosen injection site.
    2. Hold the syringe at a 45-degree angle to the skin.
    3. Insert the needle quickly and smoothly into the skin.
    4. Slowly press the plunger to inject the peptide.
    5. Withdraw the needle at the same angle and dispose of it in a sharps container.
    6. Apply gentle pressure to the site with a clean cotton pad if necessary.


**5. Post-Injection Care & Best Practices**

  • Do not rub the injection site after administering, as this may cause irritation.
    • Monitor for redness, swelling, or irritation. Mild discomfort is normal, but excessive redness or pain may indicate improper technique or sensitivity.
    • Store peptides as directed—some require refrigeration while others remain stable at room temperature.
    • Rotate injection sites to avoid irritation, scar tissue buildup, or bruising.
    • Never reuse needles; always dispose of them properly.


**6. Frequently Asked Questions (FAQs)**


**How Often Should I Rotate Injection Sites?**

To prevent tissue damage or irritation, rotate sites each injection (e.g., alternate between the abdomen, thigh, and upper arm).


**Can I Inject Peptides Intramuscularly (IM)?**

Some peptides may be administered intramuscularly (IM) depending on their intended effects. This requires a 90-degree injection angle into a large muscle (e.g., glute, thigh, or deltoid).


**What Happens If I Inject in the Wrong Spot?**

If the injection was misplaced but still subcutaneous, it will likely still be absorbed. If injected into muscle unintentionally, absorption may be faster, but it is generally not harmful.


**Can I Reuse Syringes?**

No. Always use a new, sterile syringe for each injection to avoid contamination and infection.

Key Benefits

Key Research Benefits:

  • Enhanced Cellular Growth and Proliferation: IGF-1 LR3 is integral for studies on cellular growth due to its ability to interact with the insulin-like growth factor 1 receptor (IGF-1R), promoting cell division and growth. This makes it a crucial peptide for research in tissue regeneration and muscle development.
  • Regulation of Metabolism: The peptide plays a significant role in the modulation of metabolism, providing a key tool for investigating metabolic diseases, including diabetes and growth disorders.
  • Longevity and Anti-Aging Research: IGF-1 LR3’s potential effects on lifespan and aging, particularly its role in cellular senescence and healthspan, are areas of intense scientific focus, offering possibilities for new insights into aging processes.
  • Neuroprotective Properties: Research suggests that IGF-1 LR3 may offer protective effects against neurodegenerative diseases, supporting its study in the context of brain health and cognitive functions.

Disclaimer

Usage Disclaimer

Intended Use: Research Chemical Only.

This product is strictly intended for research purposes as a chemical compound. It is designated for in vitro testing and laboratory experimentation only. All information provided on this website is for educational purposes and scientific understanding.

Legal Restrictions. By law, this product is prohibited from any form of bodily introduction into humans or animals. It is imperative that only licensed and qualified professionals handle this product in controlled laboratory settings.

Not Classified as a Drug, Food, or Cosmetic. Please note that this product is not classified as a drug, food, or cosmetic. It must not be misrepresented, misused, or mislabeled as such under any circumstances.

Possible Side Effects

Most Common Side Effects of IGF-1 LR3

  • Hypoglycemia: Low blood sugar levels, leading to symptoms like dizziness, sweating, and confusion.
     
  • Edema: Swelling in extremities due to fluid retention.
  • Joint Pain: Discomfort in joints, potentially affecting mobility.
     
  • Muscle Pain: Aches or soreness in muscles, possibly due to increased growth activity.

Headaches: Persistent head pain, which may vary in intensity.

Properties

Chemical Information of IGF-1 LR3

  • Chemical Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
  • Molecular Mass: Approximately 9,117.60 g/mol
  • Synonyms: Long R3-IGF-1, IGF-1 Long R3
  • CAS Number: 143045-27-6
  • PubChem CID: Not available
  • Total Amount of the Active Ingredient: Varies by formulation; consult specific product details.

Shelf Life: Dependent on storage conditions; refer to manufacturer guidelines.

Additional information

Weight 6 g
Dimensions .8 × .8 × 1.5 in

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